Modular Markup for Simulating Vascular Tumour Growth

Abstract

In this paper we present preliminary results of the first application of TumorML being developed outside of the context of the Transatlantic TUmor Model Repositories project (TUMOR). Based on a domain-specific software framework for developing models to simulate vascular tumour growth, we have developed a corresponding domain-specific language (DSL) for use with the framework. The DSL script is directly embedded into TumorML model descriptions serving as an example of how within a single model description document, we can fully describe cancer models as functional components. We introduce the framework that our DSL orchestrates; show fragments of DSL script we have developed to describe tumour-induced angiogenesis; and how these functional model descriptions can be integrated and executed with TumorML markup.