Anna Muszkiewicz presented a poster on "Investigating the role of ionic current changes induced by nNOS on human atrial action potential using an in silico population of models calibrated with experimental data" (A. Muszkiewicz, A. Bueno-Orovio, X. Liu, B. Casadei, B. Rodriguez) at the Oxford BHF CRE Annual Symposium 2015.
Medical Humanities Sheffield and the Computational Cardiovascular Science Team, University of Oxford, have organised a Wellcome Trust funded workshop on "Validation and Models in Computational Biomedical Science: Philosophy, Engineering and Science".
The workshop will take place at the University of Sheffield on the 30th November 2015. 30th September 2015 is the deadline for expression of interests for both workshop presentations and papers for a Special Issue in Progress in Biophysics and Molecular Biology. The invited full papers will be due on 29th February, 2016.
For more info click here or contact us:
The Lush Prize is a prestigious international award designed to support organisations working to replace animal testing with scientifically valid non-animal methods.
We have been shortlisted due to the potential of our work to replace existing animal assays in safety pharmacology and toxicology, and our specific contribution in the construction of computational models of human heart cells and tissue. These models incorporate the observed variability in experimental recordings obtained from different hearts, which enables and expands quantitative toxicological predictions incorporating inter-individual variability. We have made our research usable to a wide range of users through the Virtual Assay software, removing the need for specialised programming and mathematical experience, which will lead to increased interest from industry.
The team of international judges will meet in London in mid-September to decide on the winners for each category. Fingers crossed!!
The EU funded project “Infrastrtucture for Systems Biology Europe” (ISBE) has compiled a collection of 16 success stories, including our approach using computer models to simulate a population of heart human cells to understand differences between individuals, and the impact it might have on the reduction on animal experiments, neuroscience and diabetes.
Dr Elisa Passini has been selected as one of the recipients of the 2015 Safety Pharmacology Society Junior Travel Award. She will present her work "In silico prediction of drug effects on human ventricular electrophysiology using the Virtual Assay software and comparison to in vitro data" both as a poster and an oral communication at the Safety Pharmacology Society meeting to be held September 28-October 1, 2015 in Prague, Czech Republic.
Vicente Grau has been awarded the title of Professor of Biomedical Image Analysis at the University of Oxford, congratulations!
Alfonso Bueno-Orovio gives a talk on "In silico assessment of toxicity: from Noble’s model to an industrial solution". The Avicenna project is on its final phase as it finishes the Roadmap before the project deadline, at the end of September.
Experts gathered in Barcelona to discuss the final draft of the Roadmap, formulate the way forward for in silico Clinical Trials – in the form of the Avicenna Alliance, and hear some excellent talks from a superb line up of speakers!
Our collaborator Antonio Zaza, Professor of Physiology at Università degli Studi di Milano-Bicocca, visited us the week of the 18th-22th of May. We had time to review our recent advances in Milano and Oxford, identifying synergies and discussing future ways to continue a very fruitful collaboration.
It was a very productive week, and we thank him for coming!
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