Latest News

Special issue on Safety Pharmacology at Frontiers

Special issue on Safety Pharmacology at Frontiers

Posted 23/01/2017

Frontiers is preparing a special issue on "Safety Pharmacology, Risk Assessment QT Interval Prolongation and Beyond at Frontiers". The deadline for expression of interest it the 1st of March and for manuscripts the 1st of July. Please visit here for more information.

The editors for this special topic are; Eleonora Grandi and Stefano Morotti, (The University of California, Davis, USA) Esther Pueyo, (University of Zaragoza, Spain) and Blanca Rodriguez (University of Oxford, UK). 

The TransQST project has been officially launched.

The TransQST project has been officially launched.

Posted 23/01/2017

This new £14m European research project has been launched. The project aims at understanding adverse drug reactions and improving the approach of systems modelling for drug safety.

Funded by the Innovative Medicines Initiative 2 (IMI2) Joint Undertaking, this five-year project “Translational Quantitative Systems Toxicology (TransQST)” aims at developing novel computational approaches using the best available data from the public and private domains to address drug safety challenges.

TransQT is a partnership between ten academic institutions, including the Computational Cardiovascular Science group, three Small and Medium-sized enterprises (SMEs) and eight pharmaceutical companies. The project will be coordinated by the University of Liverpool, and the pharmaceutical company AbbVie is the Project Leader.

The kick off of meeting will be held on Monday the 23rd and Tuesday the 24th of January in Barcelona.

 

Blanca Rodriguez willl be giving several talks during Febrary

Blanca Rodriguez willl be giving several talks during Febrary

Posted 17/01/2017

Blanca Rodriguez will be giving talks at the Gordon Conference on Cardiac Arrhythmia Mechanisms in California, February 5-10, and at the Biophysical Society 61st annual Meeting in New Orleans, Louisiana, February 11-15. 

She will also be giving a seminar at Rudy’s lab, the Cardiac Bioelectricity & Arrhythmia Center (CBAC), at the Washington University in St. Louis. 

 

Michele Orini will visit us on Wednesday.

Posted 13/12/2016

Michele Orini will visit us on Wednesday to discuss new ways of collaboration and future research. Michele Orini is a Marie-Curie Research Fellow at the Institute of Cardiovascular Science, University College London, London, United Kingdom.

His research involves studying the electrical activity of the heart and some of its dysfunctions related to sudden cardiac death.

Please contact if you are interested!

Rubén Casado will be visiting us on Monday the 12th.

Posted 09/12/2016

Rubén Casado, Director of the Coronary Care Unit at the Cardiology Department Erasmus Hospital and associate Professor of Medicine, Université Libre de Bruxelles, is a researcher in the field of Cardiac Arrhythmias. 

He will be visiting us on Monday to explore ways of collaborations. 

If you are interested, please contact!

We are part of a BHF granted project.

We are part of a BHF granted project.

Posted 12/12/2016

Vicente Grau is a Co-Investigator of the BHF Project Grant “Improving risk stratification in HCM through a computational anatomical analysis of ventricular remodelling”. The project, which will start on 2017, will last 3 years and we will be working together with Kings College London. 

Oliver Britton has joined the University's 3Rs sub-committee.

Oliver Britton has joined the University's 3Rs sub-committee.

Posted 25/11/2016

Oliver Britton has joined the University's 3Rs sub-committee. This committee is involved in reviewing recent work with animals carried out within the university that might impact the 3Rs, communicating any advances across the university and organising workshops and other forms of engagement on 3Rs topics.

Congratulations! 

 

Michael A. Colman will be visiting us on Wednesday the 30th of November.

Posted 28/11/2016

Michael A. Colman, the School of Biomedical Sciences at the University of Leeds, will be visiting us on Wednesday the 30th of November. We will explore opportunities for future collaborative research projects. 

He will also be giving a talk at the Computational Biology Seminar on "From calcium sparks to fibrillation: Modelling the arrhythmic consequences of microscopic fluctuations at the organ scale" at 1 pm. 

Alfonso Bueno-Orovio will give a talk at the Comprehensive In Vitro Proarrhythmia Assay (CIPA) Update.

Alfonso Bueno-Orovio will give a talk at the Comprehensive In Vitro Proarrhythmia Assay (CIPA) Update.

Posted 24/11/2016

Alfonso Bueno-Orovio will give a talk at the the Comprehensive In Vitro Proarrhythmia Assay (CIPA) Update Meeting that will be in the Washington, DC area, on Tuesday December 6th, 2016.

The objective of the CIPA initiative is to facilitate the adoption of a new paradigm for assessment of clinical potential of TdP that is not measured exclusively by potency of hERG block and not at all by QT prolongation. This will be an important meeting to explore and get feedback on where CIPA is currently and the proposed steps over the next year. 

We will take this opportunity to discuss the advantages of in silico assays on cardiovascular research!

Hector Martinez-Navarro and Ana Minchole attended the "STAFF Meeting"

Hector Martinez-Navarro and Ana Minchole attended the "STAFF Meeting"

Posted 11/10/2016

Hector Martinez-Navarro and Ana Minchole have attended the "STAFF Meeting" held in Bled, Slovenia. Hector gave the talk entitled "Computer simulations of the human ischaemic ventricles for risk stratification and ECG biomarkers evaluation".

The STAFF Meetings popped up as an opportunity for clinicians and scientists to enhance the role of the 12-lead ECG for detection and quantification of involved myocardium in patients with acute coronary syndrome. STAFF meetings got the name from the STAFF database that comprises 228 patients undergoing elective 5 minute coronary artery balloon occlusion angioplasty at a single centre in the pre-stent era in whom standard and high frequency electrocardiographic and nuclear information was obtained immediately before, during and after balloon occlusion.

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