Latest News
Posted 27/03/2018
This event is an opportunity for industry to see the state-of-the-art in artificial intelligence and machine learning at one of the world’s great universities, and meet Oxford’s AI experts one-to-one.
Polina Mamoshina is presenting a poster on “Applications of Machine Learning in Drug Discovery”.
Posted 21/03/2018
The NC3Rs Cardiovascular Showcase event, Friday 23 March, is held in London. This event shows the wide range of NC3Rs projects within cardiovascular science and brings together a diverse group of scientists working to advance the application of the 3Rs in cardiovascular research and safety assessment. This includes NC3Rs-funded researchers and industry experts participating in NC3Rs-led working groups to stimulate changes in policy and practice.
Elisa is giving a talk entitled "In silico human-based methodologies for evaluation of drug cardiac safety and efficacy" under the session "Showcasing NC3Rs funded research: 3Rs model development in cardiovascular sciences".
Posted 15/03/2018
The National Centre for the 3Rs (NC3Rs) – an organisation dedicated to replacing, refining and reducing the use of animals in research and testing – has awarded its top prize for a research paper by the Computational Cardiovascular Science team.
The International 3Rs prize was awarded for research which developed original software that predicts the clinical risk of drug-induced side effects for the heart with higher accuracy than animal experiments.
The software is based on human data, rather than animal data: this improves how test results translate to humans and reduces the need for animal experimentation. Rather than a one-model-fits-all, this software uses a population-based approach, which is an important step towards personalised medicine.
Several companies in the pharmaceutical industry are already using the Virtual Assay software with promising results, and collaboration with industry is ongoing.
The 3Rs prize, sponsored by GSK, was presented for the research paper by Dr Elisa Passini and colleagues from the Computational Cardiovascular Science team and Janssen Pharmaceutical at a ceremony on 12 March.
The winning research builds on work by the same team, awarded the 3Rs Prize in 2014. Dr Oliver Britton and colleagues then established a computer model that incorporated variations in ‘normal’ heart electrophysiological properties based on existing data from rabbit Purkinje fibres (cardiac cells).
Virtual Assay is now available for download in the Oxford University Innovation Store: https://process.innovation.ox.ac.uk/software
The project website is at: www.cs.ox.ac.uk/insilicocardiotox/home
The prize-winning research paper: http://www.cs.ox.ac.uk/publications/publication11593-abstract.htm
Posted 20/03/2018
The CompBioMed project has created the Virtual Human film, an amazing video showing the power of supercomputers. Rendered on MareNostrum supercomputer at Barcelona Supercomputing Center, it shows how scientists can map and plan treatments in our bodies to determine the best outcome for us. How long will it be before we could all have our own Virtual Human?
On 27th September the film was launched at the London Science Museum followed by presentations from four of the Principle Investigators of the project including Prof. Peter Coveney (UCL), who leads the consortium, on simulating how drugs work in the body, Prof. Blanca Rodriguez (Oxford University), on virtual hearts, Prof. Marco Viceconti (Sheffield University), a key player in the Virtual Physiological Human initiative and Prof. Alfons Hoekstra (University of Amsterdam), on virtual blood vessels and more.
The film is now publicly available to watch here, don´t miss it!.
Posted 29/01/2018
Congratulations to Blanca Rodriguez who has received the MPLS Impact awards for the commercial impact of her group’s research on Pharmaceutical companies.
The awards are presented at the MPLS Winter Reception at 5pm on Tuesday 6 February 2018 in the Joseph Hotung Auditorium, Mansfield College.
Many congratulations Blanca!
Posted 01/02/2018
Michelangelo Paci, from the Tampere University of Technology (TUT), is visiting us from the 1st of February until the 31st of March. Michelangelo Paci is a specialist on stem cell derived cardiomyocytes and we will working together on a common research goals.
If you are interested, please contact.
Posted 20/03/2018
The international CMR community gathers this year in Barcelona, 31st January-3rd February, for the CMR 2018, a joint EuroCMR*/SCMR meeting organised by the European Association of Cardiovascular Imaging (EACVI), a registered branch of the European Society of Cardiology, and the Society for Cardiovascular Magnetic Resonance (SCMR).
CMR 2018 focuses on the theme of “Improving Clinical Value by Technical Advances”, emphasising the common goal of improving clinical outcomes in cardiovascular disease through innovation in basic MR development and medical engineering.
By providing a space where experts from all over the world with different experience and background share knowledge, the meeting offers a place for cutting-edge information both on a novice and advanced level.
Aurore Lyon is giving a talk on "Redefining risk with Artificial Intelligence" at the session "Machine Learning Artificial Intelligence and Post Processing".
Posted 22/01/2018
Tim Betts is visiting us on Friday the 26th of January. Dr Betts is a Consultant in Cardiology and Cardiac Electrophysiology at the Oxford Private Heart and Lung Centre at Nuffield Health Oxford, The Manor Hospital. He also works at the Oxford University Hospitals NHS Trust.
Posted 22/01/2018
Dr. Sanjay Kharche is visiting us on the 22nd of January to explore ways of collaboration. He is currently working at the Department of Medical Biophysics, The University of Western Ontario and in the London Health Sciences Centre, Ontario. Sanjay does research in Systems Biology, Biomedical Engineering, Cardiovascular Simulation, and Algorithms.
Posted 22/01/2018
Clint Davies Taylor is visiting us on Wednesday the 31st of January, working on Simulia Dassault Systemes. We are presenting him our work on drugs and whole heart electrophysiological models.
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