Alfonso Bueno-Orovio : Publications
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@book{Alfonso_Bueno-Orovio58676992, title = "SMOD - Data Augmentation Based on Statistical Models of Deformation to Enhance Segmentation in 2D Cine Cardiac MRI", author = "Corral Acero J and Zacur E and Xu H and Ariga R and Bueno-Orovio A and Lamata P and Grau V", year = "2019", isbn = "9783030219482", issn = "0302-9743", journal = "Functional Imaging and Modeling of the Heart", url = "http://doi.org/10.1007/978-3-030-21949-9\_39", doi = "10.1007/978-3-030-21949-9\_39", }
@article{CPT2019, title = "General principles for the validation of proarrhythmia risk prediction models: An extension of the CiPA in silico strategy", author = "Zhihua Li and Gary R Mirams and Takashi Yoshinaga and Bradley J Ridder and Xiaomei Han and Janell E Chen and Norman L Stockbridge and Todd A Wisialowski and Bruce Damiano and Stefano Severi and Pierre Morissette and Peter R Kowey and Mark Holbrook and Godfrey Smith and Randall L Rasmusson and Michael Liu and Zhen Song and Zhilin Qu and Derek J Leishman and Jill Steidl‐Nichols and Blanca Rodriguez and Alfonso Bueno‐Orovio and Xin Zhou and Elisa Passini and Andrew G Edwards and Stefano Morotti and Haibo Ni and Eleonora Grandi and Colleen E Clancy and Jamie Vandenberg and Adam Hill and Mikiko Nakamura and Thomas Singer and Liudmila Polonchuk and Andrea Greiter‐Wilke and Ken Wang and Stephane Nave and Aaron Fullerton and Eric A Sobie and Michelangelo Paci and Flora Musuamba Tshinanu and David G Strauss", year = "2019", journal = "Clinical Pharmacology & Therapeutics", doi = "10.1002/cpt.1647", }
@article{SR2019, title = "High arrhythmic risk in antero-septal acute myocardial ischemia is explained by increased transmural reentry occurrence", author = "H Martinez-Navarro and A Mincholé and A Bueno-Orovio and B Rodriguez", year = "2019", journal = "Scientific Reports", doi = "10.1038/s41598-019-53221-2", }
@article{JACC2019, title = "Electrophysiological and contractile effects of disopyramide in patients with obstructive hypertrophic cardiomyopathy: a translational study", author = "Raffaele Coppini and Cecilia Ferrantini and Josè Manuel Pioner and Lorenzo Santini and Zhinuo J Wang and Chiara Palandri and Marina Scardigli and Giulia Vitale and Leonardo Sacconi and Pierluigi Stefàno and Laura Flink and Katherine Riedy and Francesco Saverio Pavone and Elisabetta Cerbai and Corrado Poggesi and Alessandro Mugelli and Alfonso Bueno-Orovio and Iacopo Olivotto and Mark V Sherrid", year = "2019", journal = "JACC: Basic to Translational Science", doi = "10.1016/j.jacbts.2019.06.004", }
@article{Morphologie2019, title = "Improving the clinical understanding of hypertrophic cardiomyopathy by combining patient data, machine learning and computer simulations: a case study", author = "A Lyon and A Mincholé and A Bueno-Orovio and B Rodriguez", year = "2019", journal = "Morphologie", doi = "10.1016/j.morpho.2019.09.001", }
@article{BJP2019, title = "Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias", author = "Elisa Passini and Cristian Trovato and Pierre Morissette and Frederick Sannajust and Alfonso Bueno‐Orovio and Blanca Rodriguez", year = "2019", journal = "British journal of pharmacology", doi = "10.1111/bph.14786", }
@article{Alfonso_Bueno-Orovio58676492, title = "Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D", author = "Zhou X and Bueno-Orovio A and Schilling RJ and Kirkby C and Denning C and Rajamohan D and Burrage K and Tinker A and Rodriguez B and Harmer SC", year = "2019", issn = "1664-042X", journal = "Frontiers in Physiology", url = "http://doi.org/10.3389/fphys.2019.00259", doi = "10.3389/fphys.2019.00259", }
@article{Jakes_2019, title = "Perlin Noise Generation of Physiologically Realistic Patterns of Fibrosis", author = "David Jakes and Kevin Burrage and Christopher C. Drovandi and Pamela Burrage and Alfonso Bueno-Orovio and Rodrigo W. dos Santos and Blanca Rodriguez and Brodie A J Lawson", year = "2019", publisher = "Cold Spring Harbor Laboratory", url = "https://doi.org/10.1101%2F668848", doi = "10.1101/668848", }
@article{Alfonso_Bueno-Orovio58676598, title = "In silico evaluation of arrhythmia", author = "Xin Zhou and Alfonso Bueno-Orovio and Blanca Rodriguez", year = "2018", issn = "2468-8673", journal = "Current Opinion in Physiology", url = "http://doi.org/10.1016/j.cophys.2017.11.003", doi = "10.1016/j.cophys.2017.11.003", }
@article{Alfonso_Bueno-Orovio58676582, title = "From ionic to cellular variability in human atrial myocytes: an integrative computational and experimental study", author = "Muszkiewicz A and Liu X and Bueno-Orovio A and Lawson BAJ and Burrage K and Casadei B and Rodriguez B", year = "2018", issn = "0363-6135", journal = "American Journal of Physiology-Heart and Circulatory Physiology", url = "http://doi.org/10.1152/ajpheart.00477.2017", doi = "10.1152/ajpheart.00477.2017", }
@article{Alfonso_Bueno-Orovio47664652, title = "Strategies of data layout and cache writing for input-output optimization in high performance scientific computing: Applications to the forward electrocardiographic problem", author = "Louie Cardone-Noott and Blanca Rodriguez and Alfonso Bueno-Orovio", year = "2018", journal = "PLOS ONE", url = "http://doi.org/10.1371/journal.pone.0202410", doi = "10.1371/journal.pone.0202410", }
@article{Alfonso_Bueno-Orovio58676557, title = "Slow Recovery of Excitability Increases Ventricular Fibrillation Risk as Identified by Emulation", author = "Lawson BA and Burrage K and Burrage P and Drovandi CC and Bueno-Orovio A", year = "2018", issn = "1664-042X", journal = "Frontiers in Physiology", url = "http://doi.org/10.3389/fphys.2018.01114", doi = "10.3389/fphys.2018.01114", }
@article{Alfonso_Bueno-Orovio58676511, title = "Commentary: Atrial Rotor Dynamics Under Complex Fractional Order Diffusion", author = "Alfonso Bueno-Orovio", year = "2018", issn = "1664-042X", journal = "Frontiers in Physiology", url = "http://doi.org/10.3389/fphys.2018.01386", doi = "10.3389/fphys.2018.01386", }
@article{Alfonso_Bueno-Orovio58676503, title = "Electrocardiogram phenotypes in hypertrophic cardiomyopathy caused by distinct mechanisms: apico-basal repolarization gradients vs. Purkinje-myocardial coupling abnormalities", author = "Lyon A and Bueno-Orovio A and Zacur E and Ariga R and Grau V and Neubauer S and Watkins H and Rodriguez B and Minchole A.", year = "2018", issn = "1099-5129", journal = "EP Europace", url = "http://doi.org/10.1093/europace/euy226", doi = "10.1093/europace/euy226", }
@article{Alfonso_Bueno-Orovio58676925, title = "The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study", author = "Britton OJ and Bueno-Orovio A and Virág L and Varró A and Rodriguez B", year = "2017", issn = "1664-042X", journal = "Frontiers in Physiology", url = "http://doi.org/10.3389/fphys.2017.00278", doi = "10.3389/fphys.2017.00278", }
@article{Alfonso_Bueno-Orovio58676891, title = "Atrial Fibrillation Dynamics and Ionic Block Effects in Six Heterogeneous Human 3D Virtual Atria with Distinct Repolarization Dynamics", author = "Carlos Sánchez and Alfonso Bueno-Orovio and Esther Pueyo and Blanca Rodriguez", year = "2017", issn = "2296-4185", journal = "Frontiers in Bioengineering and Biotechnology", url = "http://doi.org/10.3389/fbioe.2017.00029", doi = "10.3389/fbioe.2017.00029", }
@article{Alfonso_Bueno-Orovio58676886, title = "Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity", author = "Passini E and Britton OJ and Lu HR and Rohrbacher J and Hermans AH and Gallacher DJ and Greig RJH and Bueno-Orovio A and Rodriguez B", year = "2017", issn = "1664-042X", journal = "Frontiers in Physiology", url = "http://doi.org/10.3389/fphys.2017.00668", doi = "10.3389/fphys.2017.00668", }
@article{Alfonso_Bueno-Orovio58676624, title = "Exact solutions to the fractional time-space Bloch-Torrey equation for magnetic resonance imaging", author = "Alfonso Bueno-Orovio and Kevin Burrage", year = "2017", issn = "1007-5704", journal = "Communications in Nonlinear Science and Numerical Simulation", url = "http://doi.org/10.1016/j.cnsns.2017.04.013", doi = "10.1016/j.cnsns.2017.04.013", }
@article{Liberos_2016, title = "Balance between sodium and calcium currents underlying chronic atrial fibrillation termination: An in silico inter{\textendash}subject variability study", author = "Alejandro Liberos and Alfonso Bueno-Orovio and Miguel Rodrigo and Ursula Ravens and Ismael Hernandez-Romero and Francisco Fernandez-Aviles and Maria S. Guillem and Blanca Rodriguez and Andreu M. Climent", year = "2016", journal = "Heart Rhythm", month = "aug", publisher = "Elsevier {BV}", url = "http://dx.doi.org/10.1016/j.hrthm.2016.08.028", doi = "10.1016/j.hrthm.2016.08.028", }
@article{Muszkiewicz_2016, title = "Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm", author = "Anna Muszkiewicz and Oliver J. Britton and Philip Gemmell and Elisa Passini and Carlos S{\'{a}}nchez and Xin Zhou and Annamaria Carusi and T. Alexander Quinn and Kevin Burrage and Alfonso Bueno-Orovio and Blanca Rodriguez", year = "2016", journal = "Progress in Biophysics and Molecular Biology", month = "jan", number = "1-3", pages = "115--127", publisher = "Elsevier {BV}", url = "https://doi.org/10.1016%2Fj.pbiomolbio.2015.12.002", volume = "120", doi = "10.1016/j.pbiomolbio.2015.12.002", }
@book{Alfonso_Bueno-Orovio58676957, title = "Cardiac Modeling", author = "Bueno-Orovio A and Britton O and Muszkiewicz A and Rodriguez B", year = "2016", isbn = "9780123947963", journal = "Encyclopedia of Cell Biology", url = "http://doi.org/10.1016/b978-0-12-394447-4.40014-3", doi = "10.1016/b978-0-12-394447-4.40014-3", }
@article{Alfonso_Bueno-Orovio23894299, title = "Anomalous diffusion in cardiac tissue as an index of myocardial microstructure", author = "Alfonso Bueno-Orovio and Alfonso Bueno-Orovio and Irvin Teh and Jurgen E. Schneider and Kevin Burrage and Vicente Grau", year = "2016", journal = "IEEE Transactions on Medical Imaging", url = "http://doi.org/10.1109/TMI.2016.2548503", doi = "10.1109/TMI.2016.2548503", }
@article{Alfonso_Bueno-Orovio58676945, title = "In Vivo and In Silico Investigation Into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes", author = "Xin Zhou and Alfonso Bueno-Orovio and Michele Orini and Ben Hanson and Martin Hayward and Peter Taggart and Pier D. Lambiase and Kevin Burrage and Blanca Rodriguez", year = "2016", issn = "0009-7330", journal = "Circulation Research", url = "http://doi.org/10.1161/circresaha.115.307836", doi = "10.1161/circresaha.115.307836", }
@article{Alfonso_Bueno-Orovio58676941, title = "Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase", author = "Reilly SN and Liu X and Carnicer R and Recalde A and Muszkiewicz A and Jayaram R and Carena MC and Stefanini M and Surdo NC and Wijesurenda R and Lomas O and Ratnatunga C and Sayeed R and Krasopoulos G and Rajakumar T and Bueno-Orovio A and Verheule S and Fulga TA and Rodriguez B and Schotten U and Casadei B", year = "2016", issn = "1946-6234", journal = "Science Translational Medicine", url = "http://doi.org/10.1126/scitranslmed.aac4296", doi = "10.1126/scitranslmed.aac4296", }
@article{Alfonso_Bueno-Orovio58676948, title = "Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop", author = "Rodriguez B and Carusi A and Abi-Gerges N and Ariga R and Britton O and Bub G and Bueno-Orovio A and Burton RAB and Carapella V and Cardone-Noott L and Daniels MJ and Davies MR and Dutta S and Ghetti A and Grau V and Harmer S and Kopljar I and Lambiase P and Lu HR and Mincholé A and Muszkiewicz A and Oster J and Paci M and Passini E and Severi S and Taggart P and Tinker A and Valentin J-P and Varró A and Wallman M and Zhou X", year = "2016", issn = "1099-5129", journal = "Europace", url = "http://doi.org/10.1093/europace/euv320", doi = "10.1093/europace/euv320", }
@article{Alfonso_Bueno-Orovio58676931, title = "Human ventricular activation sequence and the simulation of the electrocardiographic QRS complex and its variability in healthy and intraventricular block conditions", author = "Louie Cardone-Noott and Alfonso Bueno-Orovio and Ana Mincholé and Nejib Zemzemi and Blanca Rodriguez", year = "2016", issn = "1099-5129", journal = "EP Europace", url = "http://doi.org/10.1093/europace/euw346", doi = "10.1093/europace/euw346", }
@article{Minchol__2015, title = "{ECG}-based estimation of dispersion of {APD} restitution as a tool to stratify sotalol-induced arrhythmic risk", author = "A. Minchol{\'{e}} and A. Bueno-Orovio and P. Laguna and E. Pueyo and B. Rodriguez", year = "2015", journal = "Journal of Electrocardiology", month = "sep", number = "5", pages = "867--873", publisher = "Elsevier {BV}", url = "http://dx.doi.org/10.1016/j.jelectrocard.2015.06.006", volume = "48", doi = "10.1016/j.jelectrocard.2015.06.006", }
@article{Alfonso_Bueno-Orovio58676967, title = "Basis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada Syndrome", author = "Alfonso Bueno-Orovio and Elizabeth M. Cherry EM and Steve J. Evans and Flavio H. Fenton", year = "2015", issn = "2314-6133", journal = "BioMed Research International", url = "http://doi.org/10.1155/2015/197586", doi = "10.1155/2015/197586", }
@article{Alfonso_Bueno-Orovio21358545, title = "Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy", author = "Elisa Passini and Ana Mincholé and Raffaele Coppini and Elisabetta Cerbai and Blanca Rodriguez and Stefano Severi and Alfonso Bueno-Orovio", year = "2015", journal = "Journal of Molecular and Cellular Cardiology", url = "http://doi.org/10.1016/j.yjmcc.2015.09.003", doi = "10.1016/j.yjmcc.2015.09.003", }
@article{Alfonso_Bueno-Orovio58676953, title = "On the Order of the Fractional Laplacian in Determining the Spatio-Temporal Evolution of a Space-Fractional Model of Cardiac Electrophysiology", author = "Nicole Cusimano and Alfonso Bueno-Orovio and Ian Turner and Kevin Burrage", year = "2015", issn = "1932-6203", journal = "PLOS ONE", url = "http://doi.org/10.1371/journal.pone.0143938", doi = "10.1371/journal.pone.0143938", }
@article{buenoorovio2014, title = "Na/K pump regulation of cardiac repolarization: Insights from a systems biology approach", author = "Bueno-Orovio, A. and Sánchez, C. and Pueyo, E. and Rodriguez, B.", year = "2014", journal = "Pflugers Archiv European Journal of Physiology", number = "2", pages = "183-193", volume = "466", }
@article{buenoorovio2014, title = "Fourier spectral methods for fractional-in-space reaction-diffusion equations", author = "Bueno-Orovio, A. and Kay, D. and Burrage, K.", year = "2014", journal = "BIT Numerical Mathematics", }
@article{Alfonso_Bueno-Orovio12960384, title = "Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization", author = "Bueno-Orovio A and Kay D and Grau V and Rodriguez B and Burrage K", year = "2014", journal = "Journal of the Royal Society Interface", url = "http://doi.org/10.1098/rsif.2014.0352", doi = "10.1098/rsif.2014.0352", }
@article{AtrialVariability, title = "Inter-subject variability in human atrial action potential in sinus rhythm versus atrial fibrillation patients", author = "C. Sánchez and A. Bueno-Orovio and E. Wettwer and S. Loose and J. Simon and U. Ravens and E. Pueyo and B.Rodriguez", year = "2014", journal = "PLoS ONE", number = "8", pages = "e105897", volume = "9", doi = "10.1371/journal.pone.0105897", }
@article{Bueno2014Methods, title = "Slow Adaptation of Ventricular Repolarization as a Cause of Arrhythmia?", author = "A. Bueno-Orovio and B.M. Hanson and J.S. Gill and P. Taggart and B. Rodriguez", year = "2014", journal = "Methods of Information in Medicine", number = "4", pages = "320-323", volume = "53", doi = "10.3414/ME13-02-0039", }
@article{buenoorovio2013, title = "Population of human ventricular cell models calibrated with in vivo measurements unravels ionic mechanisms of cardiac alternans", author = "Zhou, X. and Bueno-Orovio, A. and Orini, M. and Hanson, B. and Hayward, M. and Taggart, P. and Lambiase, P.D. and Burrage, K. and Rodriguez, B.", year = "2013", journal = "Computing in Cardiology", pages = "855-858", volume = "40", }
@article{buenoorovio2013, title = "Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology", author = "Britton, O.J. and Bueno-Orovio, A. and Van Ammel, K. and Lu, H.R. and Towart, R. and Gallacher, D.J. and Rodriguez, B.", year = "2013", journal = "Proceedings of the National Academy of Sciences of the United States of America", number = "23", volume = "110", }
@article{buenoorovio2013, title = "Computational probabilistic quantification of pro-arrhythmic risk from scar and left-to-right heterogeneity in the human ventricles", author = "Wallman, M. and Bueno-Orovio, A. and Rodriguez, B.", year = "2013", journal = "Computing in Cardiology", pages = "711-714", volume = "40", }
@article{buenoorovio2013, title = "Cell repolarization variability modulates atrial fibrillation dynamics in 3D virtual human atria", author = "Sanchez, C. and Bueno-Orovio, A. and Pueyo, E. and Rodriguez, B.", year = "2013", journal = "Computing in Cardiology", pages = "911-914", volume = "40", }
@article{buenoorovio2012, title = "Continuous adjoint approach for the spalart-allmaras model in aerodynamic optimization", author = "Bueno-Orovio, A. and Castro, C. and Palacios, F. and Zuazua, E.", year = "2012", journal = "AIAA Journal", number = "3", pages = "631-646", volume = "50", }
@article{sánchez2012na+, title = "The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue", author = "C. S{\'a}nchez and A. Corrias and A. Bueno-Orovio and M. Davies and J. Swinton and I. Jacobson and P. Laguna and E. Pueyo and B. Rodr{\'\i}guez", year = "2012", journal = "American Journal of Physiology-Heart and Circulatory Physiology", number = "5", pages = "H1146--H1159", publisher = "American Physiological Society", volume = "302", doi = "10.1152/ajpheart.00668.2011", }
@article{BuenoOrovio2012, title = "In Vivo Human Left-to-Right Ventricular Differences in Rate Adaptation Transiently Increase Pro-Arrhythmic Risk Following Rate Acceleration.", author = "Bueno-Orovio A, and Hanson B, and Gill J, and Taggart P, and Rodriguez B", year = "2012", journal = "PLoS ONE", }
@article{buenoorovio2009, title = "Mapped Chebyshev pseudospectral method for the study of multiple scale phenomena", author = "Alexandrescu, A. and Bueno-Orovio, A. and Salgueiro, J.R. and Pérez-García, V.M.", year = "2009", journal = "Computer Physics Communications", number = "6", pages = "912-919", volume = "180", }
@article{buenoorovio2008, title = "Minimal model for human ventricular action potentials in tissue", author = "Bueno-Orovio, A. and Cherry, E.M. and Fenton, F.H.", year = "2008", journal = "Journal of Theoretical Biology", number = "3", pages = "544-560", volume = "253", }
@article{Alexandrescu2008, title = "Mapped Chebyshev pseudospectral method to study multiple scale phenomena", author = "Alexandrescu A and Bueno-Orovio A and Salgueiro JR and Pérez-García VM", year = "2008", journal = "Comput Phys Commun 180(6):912-9", }
@article{buenoorovio2007, title = "Enhanced box and prism assisted algorithms for computing the correlation dimension", author = "Bueno-Orovio, A. and Pérez-García, V.M.", year = "2007", journal = "Chaos, Solitons and Fractals", number = "2", pages = "509-518", volume = "34", }
@article{buenoorovio2006, title = "Spectral smoothed boundary methods: The role of external boundary conditions", author = "Bueno-Orovio, A. and Pérez-García, V.M.", year = "2006", journal = "Numerical Methods for Partial Differential Equations", number = "2", pages = "435-448", volume = "22", }
@article{buenoorovio2006, title = "Spectral methods for partial differential equations in irregular domains: The spectral smoothed boundary method", author = "Bueno-Orovio, A. and Pérez-García, V.M. and Fenton, F.H.", year = "2006", journal = "SIAM Journal on Scientific Computing", number = "3", pages = "886-900", volume = "28", }
@article{buenoorovio2006, title = "Fourier embedded domain methods: Periodic and C∞ extension of a function defined on an irregular region to a rectangle via convolution with Gaussian kernels", author = "Bueno-Orovio, A.", year = "2006", journal = "Applied Mathematics and Computation", number = "2", pages = "813-818", volume = "183", }